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Effects of levobupivacaine, ropivacaine and bupivacaine on HERG channels: stereoselective bupivacaine block

1. Levobupivacaine and ropivacaine are the pure S(−) enantiomers of N-butyl- and N-propyl-2′,6′-pipecoloxylidide, developed as less cardiotoxic alternatives to bupivacaine. In the present study, we have analysed the effects of levobupivacaine, ropivacaine and bupivacaine on HERG channels stably expr...

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Detalhes bibliográficos
Main Authors: González, Teresa, Arias, Cristina, Caballero, Ricardo, Moreno, Ignacio, Delpón, Eva, Tamargo, Juan, Valenzuela, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573604/
https://ncbi.nlm.nih.gov/pubmed/12466236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704978
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