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Down-regulation of hepatic cytochrome P450 in chronic renal failure: role of uremic mediators
1. Chronic renal failure (CRF) is associated with a decrease in liver cytochrome P450 (P450). The mechanism remains poorly understood. The present study aimed to investigate the effects of the serum of rats with CRF on liver P450. 2. Normal rat hepatocytes were incubated for 24 h with serum (concent...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573574/ https://ncbi.nlm.nih.gov/pubmed/12429576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704951 |
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