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Transport and uptake of nateglinide in Caco-2 cells and its inhibitory effect on human monocarboxylate transporter MCT1

1. Nateglinide, a novel oral hypoglycemic agent, rapidly reaches the maximum serum concentration after oral administration, suggesting that it is rapidly absorbed in the gastrointestinal tract. The aim of this work is to clarify the intestinal absorption mechanism of nateglinide by means of in vitro...

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Main Authors: Okamura, Atsuko, Emoto, Akiko, Koyabu, Noriko, Ohtani, Hisakazu, Sawada, Yasufumi
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573497/
https://ncbi.nlm.nih.gov/pubmed/12237260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704875
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