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Transport and uptake of nateglinide in Caco-2 cells and its inhibitory effect on human monocarboxylate transporter MCT1

1. Nateglinide, a novel oral hypoglycemic agent, rapidly reaches the maximum serum concentration after oral administration, suggesting that it is rapidly absorbed in the gastrointestinal tract. The aim of this work is to clarify the intestinal absorption mechanism of nateglinide by means of in vitro...

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Bibliografiske detaljer
Main Authors: Okamura, Atsuko, Emoto, Akiko, Koyabu, Noriko, Ohtani, Hisakazu, Sawada, Yasufumi
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573497/
https://ncbi.nlm.nih.gov/pubmed/12237260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704875
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