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Transport and uptake of nateglinide in Caco-2 cells and its inhibitory effect on human monocarboxylate transporter MCT1

1. Nateglinide, a novel oral hypoglycemic agent, rapidly reaches the maximum serum concentration after oral administration, suggesting that it is rapidly absorbed in the gastrointestinal tract. The aim of this work is to clarify the intestinal absorption mechanism of nateglinide by means of in vitro...

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Bibliografski detalji
Glavni autori: Okamura, Atsuko, Emoto, Akiko, Koyabu, Noriko, Ohtani, Hisakazu, Sawada, Yasufumi
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573497/
https://ncbi.nlm.nih.gov/pubmed/12237260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704875
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