NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

1. Soluble guanylyl cyclase (sGC) is the only proven receptor for the ubiquitous biological messenger nitric oxide (NO) and is intimately involved in many signal transduction pathways, most notably in regulating vascular tone and platelet function. sGC is a heterodimeric (α/ß) protein that converts...

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Autores principales: Stasch, Johannes-Peter, Schmidt, Peter, Alonso-Alija, Cristina, Apeler, Heiner, Dembowsky, Klaus, Haerter, Michael, Heil, Markus, Minuth, Torsten, Perzborn, Elisabeth, Pleiss, Ulrich, Schramm, Matthias, Schroeder, Werner, Schröder, Henning, Stahl, Elke, Steinke, Wolfram, Wunder, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573403/
https://ncbi.nlm.nih.gov/pubmed/12086987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704778
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