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Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli
Proteinase-activated receptor-1 (PAR-1) is activated by thrombin and can be selectively activated by synthetic peptides (PAR-1-activating peptide: PAR-1-AP) corresponding to the receptor's tethered ligand. PAR-1 being expressed by afferent neurons, we investigated the effects of PAR-1 agonists...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573232/ https://ncbi.nlm.nih.gov/pubmed/11877315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704568 |
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