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Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo

1. We evaluated the ability of a number of peptides based on the tethered ligand sequences of human, rat and murine proteinase-activated receptor-4 (PAR(4)), to serve as receptor-activating probes or antagonists for bioassays carried out in vitro and for in vivo models of inflammation. 2. In a rat P...

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Bibliografische gegevens
Hoofdauteurs: Hollenberg, Morley D, Saifeddine, Mahmoud, Sandhu, Sabrina, Houle, Steeve, Vergnolle, Nathalie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575414/
https://ncbi.nlm.nih.gov/pubmed/15451771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705946
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