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Proteinase activated receptor 2: role of extracellular loop 2 for ligand-mediated activation

1. Rat proteinase-activated receptor-2 (PAR(2)) variants were stably expressed in rat KNRK cells: (a) wild-type (wt)–PAR(2); (b) PAR(2)PRR, with the extracellular loop 2 (EL-2) sequence P(231)E(232)E(233)mutated to PRR and (c) PAR(2)NET, with the EL-2 sequence, PEEV changed to NETL. Cell lines were...

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Detalhes bibliográficos
Main Authors: Al-Ani, Bahjat, Saifeddine, Mahmoud, Kawabata, Atsufumi, Hollenberg, Morley D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571714/
https://ncbi.nlm.nih.gov/pubmed/10556949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702834
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