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Cyclosporin A-induced free radical generation is not mediated by cytochrome P-450
1. Reactive oxygen species (ROS) have been proposed to play a role in the side effects of the immunosuppressive drug cyclosporin A (CsA). 2. The aim of this study was to investigate whether cytochrome P-450 (CYP) dependent metabolism of CsA could be responsible for ROS generation since it has been s...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573208/ https://ncbi.nlm.nih.gov/pubmed/11861326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704544 |
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