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Detection of free radicals produced from the reaction of cytochrome P-450 with linoleic acid hydroperoxide.

The ESR spin-trapping technique was employed to investigate the reaction of rabbit cytochrome P-450 1A2 (P450) with linoleic acid hydroperoxide. This system was compared with chemical systems where FeSO4 or FeCl3 was used in place of P450. The spin trap 5, 5'-dimethyl-1-pyrroline N-oxide (DMPO)...

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Detalhes bibliográficos
Main Authors: Rota, C, Barr, D P, Martin, M V, Guengerich, F P, Tomasi, A, Mason, R P
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218956/
https://ncbi.nlm.nih.gov/pubmed/9371716
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