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Cytochrome-P450 enzymes and autoimmunity: expansion of the relationship and introduction of free radicals as the link

The Cytochrome-P-450 enzymes (CYP) are among the most important xenobiotic-metabolizing enzymes, which produce reactive oxygen species (ROS) as the result of metabolizing xenobiotics. ROS are believed to play important roles in the pathophysiology of autoimmune diseases. ROS can alter the structure...

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Detalhes bibliográficos
Autor principal: Namazi, MR
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708150/
https://ncbi.nlm.nih.gov/pubmed/19555503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1740-2557-6-4
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