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Histamine H(3)-receptor-mediated [(35)S]GTPγ[S] binding: evidence for constitutive activity of the recombinant and native rat and human H(3) receptors
1. Constitutive activity of the recombinant and native rat and human H(3) receptors (H(3)Rs) was studied using H(3)R-mediated [(35)S]GTPγ[S] binding and [(3)H]-arachidonic acid release. 2. Ciproxifan, an inverse agonist at the rat H(3)R (rH(3)R), decreased [(3)H]arachidonic acid release from CHO cel...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573152/ https://ncbi.nlm.nih.gov/pubmed/11815373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704490 |
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