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Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-α biosynthesis
1. Redox and ROS regulation of MAPK-mediated TNF-α biosynthesis is not well characterized. It was hypothesized that the involvement of the MAPK pathway in regulating LPS-mediated TNF-α secretion is redox-dependent, NF-κB-sensitive and attenuated by N-acetyl-L-cysteine (NAC) and other antioxidants. 2...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573138/ https://ncbi.nlm.nih.gov/pubmed/11815388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704467 |
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