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Phenanthrolines – a new class of CFTR chloride channel openers

1. A number of phenanthrolines and benzoquinolines were examined for their ability to activate epithelial chloride secretion by measuring short circuit current (SCC) using the mouse colon epithelium. 1,10 phenanthroline stimulated electrogenic chloride secretion with an EC(50) of 612±10 μ and a Hill...

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Hlavní autoři: Duszyk, Marek, MacVinish, Lesley, Cuthbert, Alan W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573018/
https://ncbi.nlm.nih.gov/pubmed/11606326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704328
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