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4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells

1. Calu-3 cells have been used to investigate the actions of 4-chloro-benzo[F]isoquinoline (CBIQ) on short-circuit current (SCC) in monolayers, whole-cell recording from single cells and by patch clamping. 2. CBIQ caused a sustained, reversible and repeatable increase in SCC in Calu-3 monolayers wit...

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Detalhes bibliográficos
Main Authors: Szkotak, A J, Murthy, M, MacVinish, L J, Duszyk, M, Cuthbert, A W
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574981/
https://ncbi.nlm.nih.gov/pubmed/15148241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705846
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