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Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR

BACKGROUND AND PURPOSE: Calu-3 cells are derived from serous cells of human lung submucosal glands, a prime target for therapy in cystic fibrosis (CF). Calu-3 cells can be cultured to form epithelia capable of transepithelial transport of chloride. A CF Calu-3 cell is not available. EXPERIMENTAL APP...

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Detalhes bibliográficos
Main Authors: MacVinish, L J, Cope, G, Ropenga, A, Cuthbert, A W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013912/
https://ncbi.nlm.nih.gov/pubmed/17339840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707175
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