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Phenanthrolines – a new class of CFTR chloride channel openers

1. A number of phenanthrolines and benzoquinolines were examined for their ability to activate epithelial chloride secretion by measuring short circuit current (SCC) using the mouse colon epithelium. 1,10 phenanthroline stimulated electrogenic chloride secretion with an EC(50) of 612±10 μ and a Hill...

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Détails bibliographiques
Auteurs principaux: Duszyk, Marek, MacVinish, Lesley, Cuthbert, Alan W
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573018/
https://ncbi.nlm.nih.gov/pubmed/11606326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704328
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