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Phenanthrolines – a new class of CFTR chloride channel openers

1. A number of phenanthrolines and benzoquinolines were examined for their ability to activate epithelial chloride secretion by measuring short circuit current (SCC) using the mouse colon epithelium. 1,10 phenanthroline stimulated electrogenic chloride secretion with an EC(50) of 612±10 μ and a Hill...

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Detalhes bibliográficos
Main Authors: Duszyk, Marek, MacVinish, Lesley, Cuthbert, Alan W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573018/
https://ncbi.nlm.nih.gov/pubmed/11606326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704328
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