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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

1. (−)-Cannabidiol (CBD) is a non-psychotropic component of Cannabis with possible therapeutic use as an anti-inflammatory drug. Little is known on the possible molecular targets of this compound. We investigated whether CBD and some of its derivatives interact with vanilloid receptor type 1 (VR1),...

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Библиографические подробности
Главные авторы: Bisogno, Tiziana, Hanuš, Lumír, De Petrocellis, Luciano, Tchilibon, Susanna, Ponde, Datta E, Brandi, Ines, Moriello, Aniello Schiano, Davis, John B, Mechoulam, Raphael, Di Marzo, Vincenzo
Формат: Artigo
Язык:Inglês
Опубликовано: 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573017/
https://ncbi.nlm.nih.gov/pubmed/11606325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704327
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