An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

The vanilloid receptor VR1 is a nonselective cation channel that is most abundant in peripheral sensory fibers but also is found in several brain nuclei. VR1 is gated by protons, heat, and the pungent ingredient of “hot” chili peppers, capsaicin. To date, no endogenous compound with potency at this...

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Opis bibliograficzny
Główni autorzy: Huang, Susan M., Bisogno, Tiziana, Trevisani, Marcello, Al-Hayani, Abdulmonem, De Petrocellis, Luciano, Fezza, Filomena, Tognetto, Michele, Petros, Timothy J., Krey, Jocelyn F., Chu, Constance J., Miller, Jeffrey D., Davies, Stephen N., Geppetti, Pierangelo, Walker, J. Michael, Di Marzo, Vincenzo
Format: Artigo
Język:Inglês
Wydane: The National Academy of Sciences 2002
Hasła przedmiotowe:
Biological Sciences
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC123079/
https://ncbi.nlm.nih.gov/pubmed/12060783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122196999
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