RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

1. The serotonin(2C) (5-HT(2C)) receptor couples to both phospholipase C (PLC)-inositol phosphate (IP) and phospholipase A(2) (PLA(2))-arachidonic acid (AA) signalling cascades. Agonists can differentially activate these effectors (i.e. agonist-directed trafficking of receptor stimulus) perhaps due...

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Sonraí Bibleagrafaíochta
Main Authors: Berg, Kelly A, Cropper, Jodie D, Niswender, Colleen M, Sanders-Bush, Elaine, Emeson, Ronald B, Clarke, William P
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2001
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Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572953/
https://ncbi.nlm.nih.gov/pubmed/11564657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704255
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