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RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity
1. The serotonin(2C) (5-HT(2C)) receptor couples to both phospholipase C (PLC)-inositol phosphate (IP) and phospholipase A(2) (PLA(2))-arachidonic acid (AA) signalling cascades. Agonists can differentially activate these effectors (i.e. agonist-directed trafficking of receptor stimulus) perhaps due...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572953/ https://ncbi.nlm.nih.gov/pubmed/11564657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704255 |
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