Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism

1. Thrombin, generated in the circulation during injury, cleaves proteinase-activated receptor 1 (PAR1) to stimulate plasma extravasation and granulocyte infiltration. However, the mechanism of thrombin-induced inflammation in intact tissues is unknown. We hypothesized that thrombin cleaves PAR1 on...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Garavilla, Lawrence de, Vergnolle, Nathalie, Young, Steven H, Ennes, Helena, Steinhoff, Martin, Ossovskaya, Valeria S, D'Andrea, Michael R, Mayer, Emeran A, Wallace, John L, Hollenberg, Morley D, Andrade-Gordon, Patricia, Bunnett, Nigel W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
Soggetti:
Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572861/
https://ncbi.nlm.nih.gov/pubmed/11487506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704152
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi