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In vivo evidence for K(Ca) channel opening properties of acetazolamide in the human vasculature

1. The selective carbonic anhydrase inhibitor acetazolamide is known to increase blood flow in several organs. Acetazolamide directly dilates isolated resistance arteries associated with activation of calcium-activated potassium (K(Ca)) channels. We examined both the presence and mechanism of the di...

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Detalhes bibliográficos
Main Authors: Pickkers, Peter, Hughes, Alun D, Russel, Frans G M, Thien, Theo, Smits, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572572/
https://ncbi.nlm.nih.gov/pubmed/11159693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703825
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