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In vivo evidence for K(Ca) channel opening properties of acetazolamide in the human vasculature

1. The selective carbonic anhydrase inhibitor acetazolamide is known to increase blood flow in several organs. Acetazolamide directly dilates isolated resistance arteries associated with activation of calcium-activated potassium (K(Ca)) channels. We examined both the presence and mechanism of the di...

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Autori principali: Pickkers, Peter, Hughes, Alun D, Russel, Frans G M, Thien, Theo, Smits, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572572/
https://ncbi.nlm.nih.gov/pubmed/11159693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703825
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