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In vivo evidence for K(Ca) channel opening properties of acetazolamide in the human vasculature

1. The selective carbonic anhydrase inhibitor acetazolamide is known to increase blood flow in several organs. Acetazolamide directly dilates isolated resistance arteries associated with activation of calcium-activated potassium (K(Ca)) channels. We examined both the presence and mechanism of the di...

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Bibliografiske detaljer
Main Authors: Pickkers, Peter, Hughes, Alun D, Russel, Frans G M, Thien, Theo, Smits, Paul
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572572/
https://ncbi.nlm.nih.gov/pubmed/11159693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703825
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