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Potentiation of halofantrine-induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine
1. The antimalarial drug halofantrine can prolong the QT interval and this may be enhanced by prior use of mefloquine. This possible interaction has been investigated by examining the effects of halofantrine and mefloquine alone and in combination. 2. In anaesthetized rabbits (n=6 per group), halofa...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572561/ https://ncbi.nlm.nih.gov/pubmed/11156578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703823 |
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