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Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsade de pointes
1. This study was designed to compare the proarrhythmic activity of the antimalarial drug, halofantrine and the antihistamine, terfenadine, with that of clofilium a K(+) channel blocking drug that can induce torsade de pointes. 2. Experiments were performed in pentobarbitone-anaesthetized, open-ches...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573214/ https://ncbi.nlm.nih.gov/pubmed/11861329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704550 |
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