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Evaluation of the potential for QTc prolongation with avelumab
PURPOSE: To report integrated electrocardiogram (ECG) summary and exposure–QTc analyses for avelumab, a human immunoglobulin G1 monoclonal antibody that binds programmed cell death 1 ligand 1, to assess potential effects on cardiac repolarization. METHODS: Data were pooled from three-phase 1/2 studi...
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| Publicado no: | Cancer Chemother Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6795609/ https://ncbi.nlm.nih.gov/pubmed/31478078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-019-03925-z |
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