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Rho-kinase inhibitors prevent agonist-induced vasospasm in human internal mammary artery

1. Vasospasm of arterial conduits used for coronary artery surgery is an important cause of graft failure and is likely to result partly from raised levels of vasoconstrictor substances such as thromboxane A(2) and endothelin-1. Our aim was to find pharmacological agents that could prevent agonist-i...

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Detalhes bibliográficos
Main Authors: Batchelor, Timothy J P, Sadaba, J Rafael, Ishola, Adekunle, Pacaud, Pierre, Munsch, Christopher M, Beech, David J
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572553/
https://ncbi.nlm.nih.gov/pubmed/11156590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703809
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