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Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension

A burgeoning body of evidence suggests that RhoA/Rho kinase (ROCK) signalling plays an important role in the pathogenesis of various experimental models of pulmonary hypertension (PH), including chronic hypoxia-, monocrotaline-, bleomycin-, shunt- and vascular endothelial growth factor receptor inhi...

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Detalhes bibliográficos
Main Authors: Oka, M, Fagan, K A, Jones, P L, McMurtry, I F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579659/
https://ncbi.nlm.nih.gov/pubmed/18536743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.239
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