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Suppression of the Rho/Rho-Kinase Pathway and Prevention of Cerebral Vasospasm by Combination Treatment with Statin and Fasudil After Subarachnoid Hemorrhage in Rabbit

The Rho/Rho-kinase pathway is considered important in the pathogenesis of sustained smooth muscle cell contraction during cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). The aims of this study were to investigate whether combination treatment, with pitavastatin as an inhibitor of...

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Détails bibliographiques
Auteurs principaux: Naraoka, Masato, Munakata, Akira, Matsuda, Naoya, Shimamura, Norihito, Ohkuma, Hiroki
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644406/
https://ncbi.nlm.nih.gov/pubmed/23658597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-012-0247-9
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