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Pharmacological characterization of the human 5-HT(4(d)) receptor splice variant stably expressed in Chinese hamster ovary cells

1. The recently identified C-terminal splice variant of the human 5-HT(4) receptor, the h5-HT(4(d)) receptor, was stably expressed in a CHO cell line at 493±25 fmol mg(−1) protein. We analysed its pharmacological properties by measuring binding affinities and 5-HT(4) ligand-induced cyclic AMP produc...

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Autori principali: Mialet, Jeanne, Berque-Bestel, Isabelle, Sicsic, Sames, Langlois, Michel, Fischmeister, Rodolphe, Lezoualc'h, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572397/
https://ncbi.nlm.nih.gov/pubmed/11030734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703641
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