Isolation of the serotoninergic 5-HT(4(e)) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines

1. RT–PCR technique was used to clone the human 5-HT(4(e)) receptor (h5-HT(4(e))) from heart atrium. We showed that this h5-HT(4(e)) receptor splice variant is restricted to brain and heart atrium. 2. Recombinant h5-HT(4(e)) receptor was stably expressed in CHO and C6-glial cell lines at 347 and 88 ...

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Detalhes bibliográficos
Main Authors: Mialet, Jeanne, Berque-Bestel, Isabelle, Eftekhari, Pierre, Gastineau, Monique, Giner, Mireille, Dahmoune, Yamina, Donzeau-Gouge, Patrick, Hoebeke, Johan, Langlois, Michel, Sicsic, Sames, Fischmeister, Rodolphe, Lezoualc'h, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571890/
https://ncbi.nlm.nih.gov/pubmed/10683202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703101
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