Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat

Tumour necrosis factor-α (TNF-α) and interleukin 1β (IL-1β) have been implicated in the pathogenesis of asthma. The p38 kinase inhibitor, SB 203580 inhibits TNF-α and IL-1β production in vitro and in vivo. In this study the effect of SB 203580 on allergen-induced airway TNF-α production and inflamma...

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Bibliographic Details
Main Authors:	Escott, K J, Belvisi, M G, Birrell, M A, Webber, S E, Foster, M L, Sargent, C A
Format:	Artigo
Language:	Inglês
Published:	2000
Subjects:	Special Reports
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1572335/ https://ncbi.nlm.nih.gov/pubmed/10991908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703605
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Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat

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