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Mechanism of terfenadine block of ATP-sensitive K(+) channels

1. The ATP-sensitive K(+) (K(ATP)) channel is a complex of a pore-forming inwardly rectifying K(+) channel (Kir6.2) and a sulphonylurea receptor (SUR). The aim of the present study was to gain further insight into the mechanism of block of K(ATP) channels by terfenadine. 2. Channel activity was reco...

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Detalhes bibliográficos
Main Authors: Zünkler, Bernd J, Kühne, Stephan, Rustenbeck, Ingo, Ott, Tilmann
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572237/
https://ncbi.nlm.nih.gov/pubmed/10928959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703483
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