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On the mechanism of ADP-induced alteration of sulphonylurea sensitivity in cardiac ATP-sensitive K(+) channels

1. To study the mechanism of regulation of sulphonylurea sensitivity in ATP-sensitive K(+) (K(ATP)) channels, we used the inside-out patch clamp technique in guinea-pig ventricular myocytes. 2. In the absence of nucleotides, the half maximal concentration of tolbutamide inhibition of K(ATP) channels...

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Detalhes bibliográficos
Main Authors: Miyamura, Akihiro, Kakei, Masafumi, Ichinari, Kotaro, Okamura, Midori, Oketani, Naoya, Tei, Chuwa
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572183/
https://ncbi.nlm.nih.gov/pubmed/10903984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703423
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