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Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents
1. Block of hKv1.5 channels by R-bupivacaine has been attributed to the interaction of the charged form of the drug with an intracellular receptor. However, bupivacaine is present as a mixture of neutral and charged forms both extra- and intracellularly. 2. We have studied the effects produced by th...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572085/ https://ncbi.nlm.nih.gov/pubmed/10807678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703334 |
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