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Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists

1. The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NM...

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Main Authors: Chopra, Bela, Chazot, Paul L, Stephenson, F Anne
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572047/
https://ncbi.nlm.nih.gov/pubmed/10780999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703298
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