Distinction between surmountable and insurmountable selective AT(1) receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT(1) receptors

1. CHO-K1 cells that were stably transfected with the gene for the human AT(1) receptor (CHO-AT(1) cells) were used for pharmacological studies of non-peptide AT(1) receptor antagonists. 2. In the presence of 10 mM LiCl, angiotensin II caused a concentration-dependent and long-lasting increase of in...

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Detalhes bibliográficos
Main Authors: Vanderheyden, P M L, Fierens, F L P, De Backer, J P, Fraeyman, N, Vauquelin, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571230/
https://ncbi.nlm.nih.gov/pubmed/10193788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702398
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