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G-protein activation by putative antagonists at mutant Thr(373)Lys α(2A) adrenergic receptors
1. Replacement of a threonine by a lysine at position 373 in the C-terminal portion of the third intracellular loop of the human α(2A)-adrenergic receptor (α(2A) AR) has been reported to generate a constitutively active mutant receptor in analogy with similar mutations in the α(1B) and β(2) AR (Ren...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571221/ https://ncbi.nlm.nih.gov/pubmed/10193774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702379 |
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