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Partial to complete antagonism by putative antagonists at the wild-type α(2C)-adrenoceptor based on kinetic analyses of agonist : antagonist interactions
1. Activation of the recombinant human α(2C)-adrenoceptor (α(2C) AR) by (−)-adrenaline in CHO-K1 cells transiently co-expressing a chimeric G(αq/i1) protein induced a rapid, transient Ca(2+) response with a high-magnitude followed by a low-magnitude phase which continued throughout the recorded time...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572480/ https://ncbi.nlm.nih.gov/pubmed/11090111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703726 |
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