Characterization of high affinity neurotensin receptor NTR1 in HL-60 cells and its down regulation during granulocytic differentiation

1. We investigated responses to neurotensin in human promyelocytic leukaemia HL-60 cells. 2. Neurotensin increased the cytosolic calcium concentration ([Ca(2+)](i)) in a concentration-dependent manner and also produced inositol 1,4,5-trisphosphate (InsP(3)). 3. Among the tested neurotensin analogues...

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Detalhes bibliográficos
Main Authors: Choi, Se-Young, Chae, Hee-Don, Park, Tae-Ju, Ha, Hyunjung, Kim, Kyong-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571214/
https://ncbi.nlm.nih.gov/pubmed/10193787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702378
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