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Cytoskeletal influences on nuclear shape in granulocytic HL-60 cells

BACKGROUND: During granulopoiesis in the bone marrow, the nucleus differentiates from ovoid to lobulated shape. Addition of retinoic acid (RA) to leukemic HL-60 cells induces development of lobulated nuclei, furnishing a convenient model system for nuclear differentiation during granulopoiesis. Prev...

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Autori principali: Olins, Ada L, Olins, Donald E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516025/
https://ncbi.nlm.nih.gov/pubmed/15317658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-30
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