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Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells
OBJECTIVE: Lamin B receptor (LBR) is an integral protein of the inner nuclear membrane. Recent studies have demonstrated that genetic deficiency of LBR during granulopoiesis results in hypolobulation of the mature neutrophil nucleus, as observed in human Pelger-Huët anomaly (PHA) and mouse ichthyosi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547467/ https://ncbi.nlm.nih.gov/pubmed/18495328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.03.003 |
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