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Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells

OBJECTIVE: Lamin B receptor (LBR) is an integral protein of the inner nuclear membrane. Recent studies have demonstrated that genetic deficiency of LBR during granulopoiesis results in hypolobulation of the mature neutrophil nucleus, as observed in human Pelger-Huët anomaly (PHA) and mouse ichthyosi...

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Detalhes bibliográficos
Main Authors: Zwerger, Monika, Herrmann, Harald, Gaines, Peter, Olins, Ada L., Olins, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547467/
https://ncbi.nlm.nih.gov/pubmed/18495328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.03.003
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