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Differential regulation of P2Y(11) receptor-mediated signalling to phospholipase C and adenylyl cyclase by protein kinase C in HL-60 promyelocytes

1. The regulatory mode of the P2Y(11) purinoceptor-mediated signalling cascades towards phospholipase C and adenylyl cyclase was studied in HL-60 promyelocytes. 2. Treatment with the potent P2Y(11) receptor activator dATP evoked an elevated intracellular Ca(2+) concentration ([Ca(2+)](i)) and inosit...

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Hlavní autoři: Suh, Byung-Chang, Kim, Tae-Don, Lee, Ihn-Soon, Kim, Kyong-Tai
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572341/
https://ncbi.nlm.nih.gov/pubmed/11015299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703581
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