Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population

1. Characterization of allelic variants of the TPMT gene (TPMT) responsible for changes in TPMT activity, and elucidation of the mechanism by which these alleles act, are required because of the clinical importance of this polymorphism for patients receiving thiopurine drugs. 2. We defined the mutat...

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Detaylı Bibliyografya
Asıl Yazarlar: Spire-Vayron de la Moureyre, Catherine, Debuysere, Hervé, Mastain, Bruno, Vinner, Elizabeth, Marez, Delphine, Lo Guidice, Jean-Marc, Chevalier, Dany, Brique, Serge, Motte, Kokou, Colombel, Jean-Frédéric, Turck, Dominique, Noel, Christian, Flipo, René-Marc, Pol, Annie, Lhermitte, Michel, Lafitte, Jean-Jacques, Libersa, Christian, Broly, Franck
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571045/
https://ncbi.nlm.nih.gov/pubmed/9831928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702152
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