Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk

Azathioprine (AZA), 6-mercaptopurine (6-MP), and thioguanine (TG) are thiopurine drugs. These agents are indicated for the treatment of various diseases including hematologic malignancies, inflammatory bowel disease (IBD), rheumatoid arthritis, and as immunosuppressants in solid organ transplants. T...

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Hlavní autoři: Nguyen, Christine M., Mendes, Margaret A.S., Ma, Joseph D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Evidence on Genomic Tests
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094768/
https://ncbi.nlm.nih.gov/pubmed/21593964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1236
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