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Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk

Azathioprine (AZA), 6-mercaptopurine (6-MP), and thioguanine (TG) are thiopurine drugs. These agents are indicated for the treatment of various diseases including hematologic malignancies, inflammatory bowel disease (IBD), rheumatoid arthritis, and as immunosuppressants in solid organ transplants. T...

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Detalhes bibliográficos
Main Authors: Nguyen, Christine M., Mendes, Margaret A.S., Ma, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094768/
https://ncbi.nlm.nih.gov/pubmed/21593964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1236
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