Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population

1. Characterization of allelic variants of the TPMT gene (TPMT) responsible for changes in TPMT activity, and elucidation of the mechanism by which these alleles act, are required because of the clinical importance of this polymorphism for patients receiving thiopurine drugs. 2. We defined the mutat...

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Detalhes bibliográficos
Main Authors: Spire-Vayron de la Moureyre, Catherine, Debuysere, Hervé, Mastain, Bruno, Vinner, Elizabeth, Marez, Delphine, Lo Guidice, Jean-Marc, Chevalier, Dany, Brique, Serge, Motte, Kokou, Colombel, Jean-Frédéric, Turck, Dominique, Noel, Christian, Flipo, René-Marc, Pol, Annie, Lhermitte, Michel, Lafitte, Jean-Jacques, Libersa, Christian, Broly, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571045/
https://ncbi.nlm.nih.gov/pubmed/9831928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702152
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